Source: Bioinformatics 2001 17: 44-57
Date: 2001/11/23
Speaker: 陽明生技所 林千涵
In the post-genomics era, the need of useful tools for genome annotation and bioinformatics research is very demanding. PEDANT is an reliable up-to-date genomic databases integrating both functional and structural information.
Because this system is aimed to easily extensible and allows to include custom methods, databases, and categories with minimal or no programming effort The firsr feature of PEDANT is (i) completely automatic processing of data using a wide range of bioinformatics methods, but they also have (ii) manual refinement of annotation, and furthermore (iii) automatic and manual assignment of gene products to a number of functional and structural categories, (iv) extensive hyperlinked protein reports, and (v) advanced DNA and protein viewers. With these features, by using SQL queries, it is possible to correlate a large variety of pre-computed properties of gene products encoded in complete genomes with each other and compare them with data sets of special scientific interest.
According these features they put on PEDANT, this paper shows their efforts on system architecture, processing pipeline using various bioinformatics methods, visualization, data release management, and the key value of PEDANT : functional and structural resource. It currently includes 80 genomic sequences and in many cases serves as the only source of exhaustive information on a given genome. In particular, the availability of structural predictions for over 300 000 genomic proteins makes PEDANT the most extensive structural genomics resource available on the web. At the end of paper, they demonstrate some applications using PEDANT.
Availability: The PEDANT genome analysis server is available at http://pedant.mips.biochem.mpg.de.
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