Microarray Data Analysis

2001/8/13


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目錄

Microarray Data Analysis

Lecture 3. Statistical Pattern Recognition

Classical Discrimination (classification)

Support Vector Machine (SVM)

Clustering Analysis

Clustering: What and why?

Existing Methods

Variables, Sim. Dissim. Dist.

Transformation and Dimension Reduction (PCA/SVD) (“curse of dimensionality” – Bellman 1961)

PowerPoint 簡報

Self-organizing maps

Self-organization maps (SOM) Kohonen (1982)

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Hierarchical methods

Phylogenetic-type tree

Phylogenetic-type tree / Correlation coefficient

PowerPoint 簡報

Bottom-up hierarchical clustering

Partitioning methods

pam

Gaussian mixture: FastMix Andrew W. Moore, Very Fast EM-based Mixture Model Cluster using Multiresolution kd-trees, Advances in Neural Information Processing Systems 11, (Submitted May 1998, Proceedings published May 1999).

How to select K?

How to evaluate clusters

Bootstrapping cluster analysis

Confidence interval and stability of clusters

作者:Michael Zhang

電子郵件: mzhang@cshl.org

首頁: http://argon.cshl.org/mzhang/cv.html

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