計畫說明: 鋅指模組的發現與結構預測

歷史簡述 (若想自己做個案分析,請勿按 hyperlink 看答案)

TFIIIA 5S RNA 相關文獻

Berg, J.M. (1986) Potential metal-binding domains in nucleic acid binding proteins. Science 232, 485-487.

Berg, J.M. (1988) Proposed structure for the zinc-binding domains from transcription factor IIIA and related proteins Proc. Natl. Acad. Sci. USA 85: 99-102

Ginsberg, A.M., King, B.O., and Roeder, R.G. (1984) Xenopus 5S gene transcription factor, TFIIIA: Characterization of a cDNA clone and measurement of RNA levels throughout development. Cell 39, 479-489.

Hanas, J.S., Hazuda, D.J., Bogenhagen, D.F., Wu, F.Y.H., and Wu, C.W. (1983) J. Biol. Chem. 258, 14120-14125.

Klug, A. and Rhodes, D. (1987) Zinc fingers: a novel protein motif for nucleic acid recognition. Trends Biochem. Sci. Dec. 12, 464-469.

Lee, M.S., Gippert, G.P., Soman, K.V., Case, D.A., and Wright, P.E. (1989) Three-dimensional solution structure of a single zinc finger DNA-binding domain. Science 245: 635-637

Miller, J., McLachlan, A.D., and Klug, A. (1985) Repetitive zinc-binding domains in the protein transcription factor IIIA from Xenopus oocytes. EMBO J. 4: 1609-1614

(zf cloning by PCR methods, cloning of 5S gene)

Nolte, R.T., Conlin, R.M., Harrison, S.C. and Brown, R.S. (1998) Differing roles for zinc fingers in DNA recognition: structure of a six-finger transcription factor IIIA complex. Proc. Natl. Acad. Sci. U.S.A. 95, 2938-2943

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Last updated on 11/23/01